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aroC [2019-08-07 08:55:40]
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aroC [2019-08-07 08:55:40]

3-dehydroquinate dehydratase
Locus
BSU_23080
Isoelectric point
4.90
Molecular weight
27.98 kDa
Protein length
255 aa Sequence Blast
Gene length
768 bp Sequence Blast
Function
biosynthesis of aromatic amino acids
Product
3-dehydroquinate dehydratase
Essential
no
E.C.
4.2.1.10
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of aromatic amino acids

    • Gene

    Coordinates
    2,412,706 2,413,473

    The protein

    Catalyzed reaction/ biological activity

  • 3-dehydroquinate = 3-dehydroshikimate + H2O (according to Swiss-Prot)

    • Protein family

  • type-I 3-dehydroquinase family (single member, according to UniProt)

    • Structure

  • 1GQN (from Salmonella typhi, 55% identity, 70% similarity) PubMed

    • Expression and Regulation

    Operons

    Genes
    aroC
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE23080 (aroC::erm trpC2) available at BGSC and in Jörg Stülke's lab, PubMed, upstream reverse: _UP1_CACTCGTCTCAAATCCTTTC, downstream forward: _UP4_TAGAACAATAAAAAAACTCA
  • BKK23080 (aroC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACTCGTCTCAAATCCTTTC, downstream forward: _UP4_TAGAACAATAAAAAAACTCA

    • References

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